ea0054p1 | (1) | NuclearReceptors2018
Jensen Rikke AM
, Paakinaho Ville
, Presman Diego M
, Swinstead Erin E
, Schiltz R Louis
, Ball David A
, Karpova Tatiana S
, Mandrup Susanne
, Hager Gordon L
The peroxisome proliferator-activated receptors (PPARs) display a high degree of conservation in the DNA- and ligand-binding domains. Despite these sequence similarities, the PPARs show distinct functions, even when co-expressed. Many experimental approaches have been employed to determine the molecular mechanisms that underlie their subtype-specific characteristics. However, these approaches have largely relied on cell population based studies, such as ChIP-seq. Here we have ...